Human induced pluripotent stem cells technology in treatment resistant depression: novel strategies and opportunities to unravel ketamine's fast-acting antidepressant mechanisms

• Main Authors: Matteo Marcatili (Author), Carlo Sala (Author), Antonios Dakanalis (Author), Fabrizia Colmegna (Author), Armando D'Agostino (Author), Orsola Gambini (Author), Bernardo Dell'Osso (Author), Beatrice Benatti (Author), Luciano Conti (Author), Massimo Clerici (Author)
• Format: Book
• Published: SAGE Publishing, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Approximately 30% of Major Depressive Disorder (MDD) patients develop treatment-resistant depression (TRD). Among the different causes that make TRD so challenging in both clinical and research contexts, major roles are played by the inadequate understanding of MDD pathophysiology and the limitation...