Structural and Functional Validation of a Full-Thickness Self-Assembled Skin Equivalent for Disease Modeling

• Main Authors: Bo Ram Mok (Author), Su-Ji Shon (Author), A Ram Kim (Author), Carolyne Simard-Bisson (Author), Israël Martel (Author), Lucie Germain (Author), Dong Hyun Kim (Author), Jung U Shin (Author)
• Format: Book
• Published: MDPI AG, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Recently, various types of in vitro-reconstructed 3D skin models have been developed for drug testing and disease modeling. Herein, we structurally and functionally validated a self-assembled reconstructed skin equivalent (RSE) and developed an IL-17a-induced in vitro psoriasis-like model using a se...