Generating mouse models for biomedical research: technological advances

• Asıl Yazarlar: Channabasavaiah B. Gurumurthy (Yazar), Kevin C. Kent Lloyd (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: The Company of Biologists, 2019-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Over the past decade, new methods and procedures have been developed to generate genetically engineered mouse models of human disease. This At a Glance article highlights several recent technical advances in mouse genome manipulation that have transformed our ability to manipulate and study gene exp...