Repurposing ibuprofen-loaded microemulsion for the management of Alzheimer's disease: evidence of potential intranasal brain targeting

• Principais autores: Ming Ming Wen (Autor), Noha Ismail Khamis Ismail (Autor), Maha M. A. Nasra (Autor), Amal Hassan El-Kamel (Autor)
• Formato: Livro
• Publicado em: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Studies have shown the use of non-steroidal anti-inflammatory drugs, such as ibuprofen could reduce the risk of Alzheimer's disease. The drug-repurposing strategy offers a bright opportunity for these patients. Intranasal administration through the olfactory pathway provides noninvasive and dir...