From understanding cellular function to novel drug discovery: the role of planar patch-clamp array chip technology

• Main Authors: Christophe ePy (Author), Marzia eMartina (Author), Gerardo A Diaz-Quijada (Author), Collin C Luk (Author), Dolores eMartinez (Author), Mike W Denhoff (Author), Anne eCharrier (Author), Tanya eComas (Author), Robert eMonette (Author), Anthony eKrantis (Author), Naweed I Syed (Author), Geoffrey A.R. Mealing (Author)
• Format: Book
• Published: Frontiers Media S.A., 2011-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

All excitable cell functions rely upon ion channels that are embedded in their plasma membrane. Perturbations of ion channel structure or function result in pathologies ranging from cardiac dysfunction to neurodegenerative disorders. Consequently, to understand the functions of excitable cells and t...