Co-Amorphization of Acemetacin with Basic Amino Acids as Co-Formers for Solubility Improvement and Gastric Ulcer Mitigation

Acemetacin (ACM) is a new non-steroidal anti-inflammatory drug with anti-inflammatory, analgesic, and antipyretic effects. However, the poor water solubility and gastrointestinal side effects limit its use. Recently, the co-amorphous (CAM) strategy has attracted great interest to improve solubility...

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Main Authors: Jiayue Hou (Author), Peixu Zhao (Author), Yanfei Wang (Author), Xiwei Jiang (Author), Qiang Fu (Author)
Format: Book
Published: MDPI AG, 2024-05-01T00:00:00Z.
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3rd Floor Main Library

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