An adaptive detection method for fetal chromosomal aneuploidy using cell-free DNA from 447 Korean women

• Main Authors: Sunshin Kim (Author), HeeJung Jung (Author), Sung Hee Han (Author), SeungJae Lee (Author), JeongSub Kwon (Author), Min Gyun Kim (Author), Hyungsik Chu (Author), Kyudong Han (Author), Hwanjong Kwak (Author), Sunghoon Park (Author), Hee Jae Joo (Author), Minae An (Author), Jungsu Ha (Author), Kyusang Lee (Author), Byung Chul Kim (Author), Hailing Zheng (Author), Xinqiang Zhu (Author), Hongliang Chen (Author), Jong Bhak (Author)
• Format: Book
• Published: BMC, 2016-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Noninvasive prenatal testing (NIPT) using massively parallel sequencing of cell-free DNA (cfDNA) is increasingly being used to predict fetal chromosomal abnormalities. However, concerns over erroneous predictions which occur while performing NIPT still exist in pregnant women at...