Analysis of the PvuII and XbaI polymorphisms in the estrogen receptor alpha gene in girls with central precocious puberty: a pilot study

• Main Authors: José Maria Soares-Jr (Author), Felisbela Soares de Holanda (Author), Cézar Noboru Matsuzaki (Author), Isabel Cristina Esposito Sorpreso (Author), Eduardo Carvalho de Arruda Veiga (Author), Luiz Carlos de Abreu (Author), Kátia Cândido Carvalho (Author), Edmund Chada Baracat (Author)
• Format: Book
• Published: BMC, 2018-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Precocious puberty (PP) is defined as premature pubertal development. Its consequences surpass the physical evidence of sexual maturity with the premature epiphyseal closure of the long bones and the reduction of adult stature by varied degrees. Central PP is characteristically d...