Assessment of contribution of BCRP to intestinal absorption of various drugs using portal‐systemic blood concentration difference model in mice

Abstract Prediction of the intestinal absorption of new chemical entities (NCEs) is still difficult, in part because drug efflux transporters, including breast cancer resistance protein (BCRP) and P‐glycoprotein (P‐gp), restrict their intestinal permeability. We have demonstrated that the absorptive...

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Main Authors: Iichiro Kawahara (Author), Satoyo Nishikawa (Author), Akira Yamamoto (Author), Yusuke Kono (Author), Takuya Fujita (Author)
Format: Book
Published: Wiley, 2020-02-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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