Bellidifolin Ameliorates Isoprenaline-Induced Myocardial Fibrosis by Regulating TGF-β1/Smads and p38 Signaling and Preventing NR4A1 Cytoplasmic Localization

• Main Authors: Hong-Xia Yang (Author), Jia-Huan Sun (Author), Ting-Ting Yao (Author), Yuan Li (Author), Geng-Rui Xu (Author), Chuang Zhang (Author), Xing-Chao Liu (Author), Wei-Wei Zhou (Author), Qiu-Hang Song (Author), Yue Zhang (Author), Ai-Ying Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Myocardial fibrosis is closely related to high morbidity and mortality. In Inner Mongolia, Gentianella amarella subsp. acuta (Michx.) J.M.Gillett (G. acuta) is a kind of tea used to prevent cardiovascular diseases. Bellidifolin (BEL) is an active xanthone molecule from G. acuta that protects against...