Possible Involvement of TLRs and Hemichannels in Stress-Induced CNS Dysfunction via Mastocytes, and Glia Activation

• Autores principales: Adam Aguirre (Autor), Carola J. Maturana (Autor), Paloma A. Harcha (Autor), Juan C. Sáez (Autor)
• Formato: Libro
• Publicado: Hindawi Limited, 2013-01-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

In the central nervous system (CNS), mastocytes and glial cells (microglia, astrocytes and oligodendrocytes) function as sensors of neuroinflammatory conditions, responding to stress triggers or becoming sensitized to subsequent proinflammatory challenges. The corticotropin-releasing hormone and glu...