Desensitization by Different Strategies of Epidermal Growth Factor Receptor and ErbB4

• Main Authors: Hideyuki Yamamoto (Author), Sayomi Higa-Nakamine (Author), Nobuhiro Noguchi (Author), Noriko Maeda (Author), Yutaka Kondo (Author), Seikichi Toku (Author), Ichiro Kukita (Author), Kazuhiro Sugahara (Author)
• 格式: 图书
• 出版: Elsevier, 2014-01-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Four transmembrane tyrosine kinases constitute the ErbB protein family: epidermal growth factor receptor (EGFR) or ErbB1, ErbB2, ErbB3, and ErbB4. In general, the structure and mechanism of the activation of these members are similar. However, significant differences in homologous desensitization ar...