Influence of Mild Chronic Stress and Social Isolation on Acute Ozone-Induced Alterations in Stress Biomarkers and Brain-Region-Specific Gene Expression in Male Wistar-Kyoto Rats

• Main Authors: Matthew C. Valdez (Author), Danielle L. Freeborn (Author), Joseph M. Valdez (Author), Andres R. Henriquez (Author), Samantha J. Snow (Author), Thomas W. Jackson (Author), Prasada Rao S. Kodavanti (Author), Urmila P. Kodavanti (Author)
• Format: Book
• Published: MDPI AG, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Individuals with psychosocial stress often experience an exaggerated response to air pollutants. Ozone (O₃) exposure has been associated with the activation of the neuroendocrine stress-response system. We hypothesized that preexistent mild chronic stress plus social isolation...