Strategies that regulate LSD1 for novel therapeutics

• Main Authors: Meng Li (Author), Mengge Dai (Author), Bing Cheng (Author), Shaotong Li (Author), Enhui Guo (Author), Junwei Fu (Author), Ting Ma (Author), Bin Yu (Author)
• Format: Bog
• Udgivet: Elsevier, 2024-04-01T00:00:00Z.
• Fag: article
• Online adgang: Connect to this object online.

Histone methylation plays crucial roles in regulating chromatin structure and gene transcription in epigenetic modifications. Lysine-specific demethylase 1 (LSD1), the first identified histone demethylase, is universally overexpressed in various diseases. LSD1 dysregulation is closely associated wit...