Strategies that regulate LSD1 for novel therapeutics
Histone methylation plays crucial roles in regulating chromatin structure and gene transcription in epigenetic modifications. Lysine-specific demethylase 1 (LSD1), the first identified histone demethylase, is universally overexpressed in various diseases. LSD1 dysregulation is closely associated wit...
Saved in:
Main Authors: | Meng Li (Author), Mengge Dai (Author), Bing Cheng (Author), Shaotong Li (Author), Enhui Guo (Author), Junwei Fu (Author), Ting Ma (Author), Bin Yu (Author) |
---|---|
Format: | Book |
Published: |
Elsevier,
2024-04-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Biological and therapeutic role of LSD1 in Alzheimer's diseases
by: Yu Li, et al.
Published: (2022) -
Natural products as LSD1 inhibitors for cancer therapy
by: Yuan Fang, et al.
Published: (2021) -
Development of the triazole-fused pyrimidine derivatives as highly potent and reversible inhibitors of histone lysine specific demethylase 1 (LSD1/KDM1A)
by: Zhonghua Li, et al.
Published: (2019) -
Discovery of novel sulphonamide hybrids that inhibit LSD1 against bladder cancer cells
by: Jia Liu, et al.
Published: (2022) -
Histone demethylase LSD1-mediated repression of GATA-2 is critical for erythroid differentiation
by: Guo Y, et al.
Published: (2015)