Targeting fibroblast growth factor (FGF)-inducible 14 (Fn14) for tumor therapy

• Główni autorzy: Olena Zaitseva (Autor), Annett Hoffmann (Autor), Christoph Otto (Autor), Harald Wajant (Autor)
• Format: Książka
• Wydane: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Fibroblast growth factor-inducible 14 (Fn14) is a member of the tumor necrosis factor (TNF) receptor superfamily (TNFRSF) and is activated by its ligand TNF-like weak inducer of apoptosis (TWEAK). The latter occurs as a homotrimeric molecule in a soluble and a membrane-bound form. Soluble TWEAK (sTW...