Gabapentin and Duloxetine Prevent Oxaliplatin- and Paclitaxel-Induced Peripheral Neuropathy by Inhibiting Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Phosphorylation in Spinal Cords of Mice

• Główni autorzy: Natsuki Kato (Autor), Keisuke Tateishi (Autor), Masanobu Tsubaki (Autor), Tomoya Takeda (Autor), Mikihiro Matsumoto (Autor), Katsumasa Tsurushima (Autor), Toshihiko Ishizaka (Autor), Shozo Nishida (Autor)
• Format: Książka
• Wydane: MDPI AG, 2020-12-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Chemotherapy-induced peripheral neuropathy is a common factor in limiting therapy which can result in therapy cessation or dose reduction. Gabapentin, a calcium channel inhibitor, and duloxetine, a serotonin noradrenaline reuptake inhibitor, are used to treat a variety of pain conditions such as chr...