Identification of the Target for a Transition Metal-α-Amino Acid Complex Antibiotic Against Mycobacterium smegmatis

Spontaneous mutants of Mycobacterium smegmatis strain mc2155 resistant to 1-PG (iridium-L-phenylglycine complex), an antimycobacterial antibiotic, were isolated. Based on the discovery that some 1-PG-resistant mutants (1-PGR) were also resistant to high concentrations of clarithromycin (≥250 μg/ml),...

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Bibliographic Details
Main Authors: George W. Karpin (Author), Joseph S. Merola (Author), Joseph O. Falkinham (Author)
Format: Book
Published: Frontiers Media S.A., 2021-06-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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