Improved early development of porcine cloned embryos by treatment with quisinostat, a potent histone deacetylase inhibitor

• Main Authors: Anukul TAWEECHAIPAISANKUL (Author), Jun-Xue JIN (Author), Sanghoon LEE (Author), Geon A KIM (Author), Yoon Ho SUH (Author), Min Seok AHN (Author), Se Jun PARK (Author), Byeong You LEE (Author), Byeong Chun LEE (Author)
• Format: Book
• Published: The Society for Reproduction and Development, 2018-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Recently, the modification of the epigenetic status of somatic cell nuclear transfer (SCNT) embryos by treatment with histone deacetylase inhibitors (HDACis) has made it possible to alter epigenetic traits and improve the developmental competence of these embryos. In the current study, we examined t...