Independent Origin and Global Distribution of Distinct Plasmodium vivax Duffy Binding Protein Gene Duplications.

• Main Authors: Jessica B Hostetler (Author), Eugenia Lo (Author), Usheer Kanjee (Author), Chanaki Amaratunga (Author), Seila Suon (Author), Sokunthea Sreng (Author), Sivanna Mao (Author), Delenasaw Yewhalaw (Author), Anjali Mascarenhas (Author), Dominic P Kwiatkowski (Author), Marcelo U Ferreira (Author), Pradipsinh K Rathod (Author), Guiyun Yan (Author), Rick M Fairhurst (Author), Manoj T Duraisingh (Author), Julian C Rayner (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Plasmodium vivax causes the majority of malaria episodes outside Africa, but remains a relatively understudied pathogen. The pathology of P. vivax infection depends critically on the parasite's ability to recognize and invade human erythrocytes. This invasion process involves an inte...