Simultaneous Activation of Erk1/2 and Akt Signaling is Critical for Formononetin-Induced Promotion of Endothelial Function

• Main Authors: Jinjun Wu (Author), Muyan Kong (Author), Yanmei Lou (Author), Leyan Li (Author), Chunlin Yang (Author), Huifang Xu (Author), Yuqi Cui (Author), Hong Hao (Author), Zhenguo Liu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Formononetin (FMNT) is a major bioactive compound from Astragalus membranaceus (Fisch.) Bunge, and has been widely used to treat conditions related to vascular insufficiency. However, the molecular mechanism for the therapeutic effect has not been well defined. This study aimed to investigate the ef...