Biodegradable Carriers for Delivery of VEGF Plasmid DNA for the Treatment of Critical Limb Ischemia

Biodegradable Carriers for Delivery of VEGF Plasmid DNA for the Treatment of Critical Limb Ischemia

The safe and efficient delivery of therapeutic nucleic acid is a prerequisite for an effective DNA therapy. In this study, we condensed the low molecular weight polyethylenimine (PEI, 1.8k Da) with 2,6-pyridinedicarboxaldehyde (PDA), both of which are degradable in vivo, to synthesize a biodegradabl...

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Bibliographic Details
Main Authors: Guang Liu (Author), Zhiwei Fang (Author), Minglu Yuan (Author), Weimin Li (Author), Yunqi Yang (Author), Mier Jiang (Author), Yuanming Ouyang (Author), Weien Yuan (Author)
Format: Book
Published: Frontiers Media S.A., 2017-08-01T00:00:00Z.
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