HIF-1α Is Associated with Resistance to Hypoxia-Induced Apoptosis in Ameloblastoma

• Main Authors: Katherine Julissa Palma Valladares (Author), Karolyny Martins Balbinot (Author), Antonia Taiane Lopes de Moraes (Author), Maria Sueli da Silva Kataoka (Author), Aline Maria Pereira Cruz Ramos (Author), Rommel Thiago Jucá Ramos (Author), Artur Luiz da Costa da Silva (Author), Ricardo Alves Mesquita (Author), David Normando (Author), Sérgio de Melo Alves Júnior (Author), João de Jesus Viana Pinheiro (Author)
• Format: Bog
• Udgivet: Hindawi Limited, 2021-01-01T00:00:00Z.
• Fag: article
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Background. Ameloblastoma (AMB) is a benign odontogenic tumour, with an aggressive local behaviour and a high rate of recurrence. Previous studies have demonstrated that hypoxia-induced factor alpha 1 (HIF-1α) and activated caspase-3 contribute to tumour invasiveness and cytogenesis in ameloblastoma...