Efficient circular RNA engineering by end-to-end self-targeting and splicing reaction using Tetrahymena group I intron ribozyme

• Główni autorzy: Kyung Hyun Lee (Autor), Seongcheol Kim (Autor), Jaehwi Song (Autor), Seung Ryul Han (Autor), Ji Hyun Kim (Autor), Seong-Wook Lee (Autor)
• Format: Książka
• Wydane: Elsevier, 2023-09-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Circular RNA (circRNA) has various advantages over linear mRNA that is gaining success as a new vaccine and therapeutic agent. Thus, circRNA and its engineering methods have attracted attention recently. In this study, we developed a new in vitro circRNA engineering method by end-to-end self-targeti...