Efficient circular RNA engineering by end-to-end self-targeting and splicing reaction using Tetrahymena group I intron ribozyme

• Auteurs principaux: Kyung Hyun Lee (Auteur), Seongcheol Kim (Auteur), Jaehwi Song (Auteur), Seung Ryul Han (Auteur), Ji Hyun Kim (Auteur), Seong-Wook Lee (Auteur)
• Format: Livre
• Publié: Elsevier, 2023-09-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Circular RNA (circRNA) has various advantages over linear mRNA that is gaining success as a new vaccine and therapeutic agent. Thus, circRNA and its engineering methods have attracted attention recently. In this study, we developed a new in vitro circRNA engineering method by end-to-end self-targeti...