Untargeted metabolomics of pulmonary tuberculosis patient serum reveals potential prognostic markers of both latent infection and outcome

• Main Authors: Xuezhi Wang (Author), Zhuhua Wu (Author), Jincheng Zeng (Author), Yuchuan Zhao (Author), Chenchen Zhang (Author), Meiling Yu (Author), Wei Wang (Author), Xunxun Chen (Author), Liang Chen (Author), Jiawen Wang (Author), Liuyue Xu (Author), Jie Zhou (Author), Qiuchan Tan (Author), Wenjing Wei (Author), Yanxia Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Currently, there are no particularly effective biomarkers to distinguish between latent tuberculosis infection (LTBI) and active pulmonary tuberculosis (PTB) and evaluate the outcome of TB treatment. In this study, we have characterized the changes in the serum metabolic profiles caused by Mycobacte...