Effects of Shenling Baizhu powder on pyrotinib-induced diarrhea: analysis of gut microbiota, metabonomics, and network pharmacology

• Main Authors: Jingjiang Lai (Author), Fengxian Jiang (Author), Xiaoli Zhuo (Author), Xiaoying Xu (Author), Lei Liu (Author), Ke Yin (Author), Jingliang Wang (Author), Jing Zhao (Author), Wei Xu (Author), Hongjing Liu (Author), Xuan Wang (Author), Wen Jiang (Author), Ke Wang (Author), Shuping Yang (Author), Honglin Guo (Author), Fanghua Qi (Author), Xiaotian Yuan (Author), Xiaoyan Lin (Author), Guobin Fu (Author)
• Format: Book
• Published: BMC, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Shenling Baizhu Powder (SBP) is a traditional Chinese medicine (TCM) prescription, which has the good efficacy on gastrointestinal toxicity. In this study, we used gut microbiota analysis, metabonomics and network pharmacology to investigate the therapeutic effect of SBP on pyrot...