Endangered Lymphocytes: The Effects of Alloxan and Streptozotocin on Immune Cells in Type 1 Induced Diabetes

• Main Authors: Luiz A. D. Queiroz (Author), Josiane B. Assis (Author), João P. T. Guimarães (Author), Emanuella S. A. Sousa (Author), Anália C. Milhomem (Author), Karen K. S. Sunahara (Author), Anderson Sá-Nunes (Author), Joilson O. Martins (Author)
• Format: Book
• Published: Hindawi Limited, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Alloxan (ALX) and streptozotocin (STZ) are extensively used to induce type 1 diabetes (T1D) in animal models. This study is aimed at evaluating the differences in immune parameters caused by ALX and STZ. T1D was induced either with ALX or with STZ, and the animals were followed for up to 180 days. B...