Design of an innovative nanovehicle to enhance brain permeability of a novel 5-HT6 receptor antagonist

An innovative nanovehicle based on lipid nanocapsules (LNC) was designed to facilitate the passage of a new 5-HT6 receptor antagonist, namely PUC-10, through the blood-brain barrier. PUC-10 is a new synthetic N-arylsulfonylindole that has demonstrated potent 5-HT6 receptor antagonist activity, but i...

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Main Authors: María Javiera Alvarez-Figueroa (Author), Francisco Nuñez-Navarro (Author), Gonzalo Recabarren-Gajardo (Author), José Vicente González-Aramundiz (Author)
Format: Book
Published: Elsevier, 2024-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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