Inter- and intra-host sequence diversity reveal the emergence of viral variants during an overwintering epidemic caused by dengue virus serotype 2 in southern Taiwan.

• Κύριοι συγγραφείς: Hui-Ying Ko (Συγγραφέας), Yao-Tsun Li (Συγγραφέας), Day-Yu Chao (Συγγραφέας), Yun-Cheng Chang (Συγγραφέας), Zheng-Rong T Li (Συγγραφέας), Melody Wang (Συγγραφέας), Chuan-Liang Kao (Συγγραφέας), Tzai-Hung Wen (Συγγραφέας), Pei-Yun Shu (Συγγραφέας), Gwong-Jen J Chang (Συγγραφέας), Chwan-Chuen King (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Public Library of Science (PLoS), 2018-10-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Purifying selection during dengue viral infection has been suggested as the driving force of viral evolution and the higher complexity of the intra-host quasi-species is thought to offer an adaptive advantage for arboviruses as they cycle between arthropod and vertebrate hosts. However, very few stu...