The use of carglumic acid in hyperammonemia secondary to bacterial overgrowth in lately diagnosed Hirschsprung disease

• Main Authors: Tala Shalakhti (Author), Yazan O. Al Zu'bi (Author), Ahmed H. Al Sharie (Author), Ahmad K. Abdulraheem (Author), Amjad Al-Salhi (Author), Ahmed N. Barakat (Author), Eyad Altamimi (Author)
• Format: Book
• Published: Elsevier, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hirschsprung disease is associated with significant bacterial proliferation and colonic dysbiosis leading to life threating hyperammonemia. In this report, we highlight the use of carglumic acid; a synthetic ammonia scavenger in hyperammonemia secondary to bacterial overgrowth in Hirschsprung diseas...