Population Pharmacokinetic and Pharmacodynamic Modeling of Acetazolamide in Peritoneal Dialysis Patients and Healthy Volunteers

• Main Authors: Corinne Seng Yue (Author), Huu Hung Huynh (Author), Catherine Raymond (Author), Louise Charbonneau (Author), Louise Roy (Author)
• Format: Book
• Published: Frontiers Media S.A., 2013-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose. To characterize the pharmacokinetics (PK) and pharmacodynamics (PD) of acetazolamide (ACTZ) in peritoneal dialysis patients, ACTZ 500 mg was administered intravenously to 7 healthy subjects (HV) and 8 peritoneal dialysis patients (CAPD). Methods. Population PK/PD modeling was performed with...