Population Pharmacokinetic and Pharmacodynamic Modeling of Acetazolamide in Peritoneal Dialysis Patients and Healthy Volunteers

• Автори: Corinne Seng Yue (Автор), Huu Hung Huynh (Автор), Catherine Raymond (Автор), Louise Charbonneau (Автор), Louise Roy (Автор)
• Формат: Книга
• Опубліковано: Frontiers Media S.A., 2013-04-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Purpose. To characterize the pharmacokinetics (PK) and pharmacodynamics (PD) of acetazolamide (ACTZ) in peritoneal dialysis patients, ACTZ 500 mg was administered intravenously to 7 healthy subjects (HV) and 8 peritoneal dialysis patients (CAPD). Methods. Population PK/PD modeling was performed with...