Effect of Piper cubeba total extract and isolated lignans on head and neck cancer cell lines and normal fibroblasts

• Main Authors: Juliana Prado Gusson-Zanetoni (Author), Julliene Stephanie Guaraldi Monteiro da Silva (Author), Thais Bravo Picão (Author), Laila Toniol Cardin (Author), Janesly Prates (Author), Stefanie Oliveira Sousa (Author), Tiago Henrique (Author), Sonia Maria Oliani (Author), Eloiza Helena Tajara (Author), Marcio Luis Andrade e Silva (Author), Nayanne Larissa Cunha (Author), Ana Carolina da Silva Gomes (Author), Rosangela Silva Laurentiz (Author), Flávia Cristina Rodrigues-Lisoni (Author)
• Format: Book
• Published: Elsevier, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The objective of the present study was to evaluate the action of the crude hydroalcoholic extract of Piper cubeba fruits and isolated lignans (cubebin, dihydrocubebin, ethylcubebin, hinokinin and methylcubebin) on head and neck cancer cells. We evaluated the influence of the Piper cubeba extract and...