A Subanesthetic Dose of Isoflurane during Postconditioning Ameliorates Zymosan-Induced Neutrophil Inflammation Lung Injury and Mortality in Mice

• Main Authors: Hui Wang (Author), Jing Fan (Author), Nan-lin Li (Author), Jun-tang Li (Author), Shi-fang Yuan (Author), Jun Yi (Author), Ling Wang (Author), Jiang-hao Chen (Author), Yong-gang Lv (Author), Qing Yao (Author), Ting Wang (Author), Yu-cai Wang (Author), Rui Ling (Author)
• Format: Book
• Published: Hindawi Limited, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Anesthetic isoflurane (ISO) has immunomodulatory effects. In the present study, we investigated whether a subanesthetic dose of ISO (0.7%) protected against zymosan (ZY) induced inflammatory responses in the murine lung and isolated neutrophils. At 1 and 6 hrs after ZY administration intraperitoneal...