Brusatol Derivative-34 Attenuates Allergic Airway Inflammation Via Inhibition of the Spleen Tyrosine Kinase Pathway

• Main Authors: Yasi Ding (Author), Weibin Tang (Author), Fei Pei (Author), Lixia Fu (Author), Pei Ma (Author), Jinye Bai (Author), Mingbao Lin (Author), Yunbao Liu (Author), Qi Hou (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Brusatol derivative-34 (Bru-34), a derivative of brusatol, has been shown significantly anti-inflammatory activity in mice in our previously work. However, to our knowledge, there were very limited studies on how Bru-34 affected airway inflammation. Thus, in this present study, the effects and poten...