Photobinding of Triflusal to Human Serum Albumin Investigated by Fluorescence, Proteomic Analysis, and Computational Studies

• Váldodahkkit: Oscar Molins-Molina (Dahkki), Raúl Pérez-Ruiz (Dahkki), Emilio Lence (Dahkki), Concepción González-Bello (Dahkki), Miguel A. Miranda (Dahkki), M. Consuelo Jiménez (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Frontiers Media S.A., 2019-09-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Triflusal is a platelet antiaggregant employed for the treatment and prevention of thromboembolic diseases. After administration, it is biotransformed into its active metabolite, the 2-hydroxy-4-trifluoromethylbenzoic acid (HTB). We present here an investigation on HTB photobinding to human serum al...