Influence of Surface Ligand Density and Particle Size on the Penetration of the Blood-Brain Barrier by Porous Silicon Nanoparticles

• Egile Nagusiak: Weisen Zhang (Egilea), Douer Zhu (Egilea), Ziqiu Tong (Egilea), Bo Peng (Egilea), Xuan Cheng (Egilea), Lars Esser (Egilea), Nicolas H. Voelcker (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2023-09-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Overcoming the blood-brain barrier (BBB) remains a significant challenge with regard to drug delivery to the brain. By incorporating targeting ligands, and by carefully adjusting particle sizes, nanocarriers can be customized to improve drug delivery. Among these targeting ligands, transferrin stand...