Cognitive impairment in children with 5q-associated spinal muscular atrophy type 1: two case reports and the review of the literature

• Main Authors: Hua Yang (Author), Jie Yang (Author), Yawen Xue (Author), Lihui Liao (Author), Qianyun Cai (Author), Rong Luo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Spinal muscular atrophy (SMA) is an autosomal recessive disease caused by mutations in the survival motor neuron 1 (SMN1) gene on chromosome 5, leading to the degeneration of lower motor neurons. There are few studies on cognitive impairment comorbid with SMA. Here, we report two cases of severe cog...