Evaluation of JQ1 Combined With Docetaxel for the Treatment of Prostate Cancer Cells in 2D- and 3D-Culture Systems

• Main Authors: Yipeng Xu (Author), Gabriela Pachnikova (Author), Dorothea Przybilla (Author), Reinhold Schäfer (Author), Yingying Cui (Author), Dan Zhou (Author), Zihao Chen (Author), An Zhao (Author), Ulrich Keilholz (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Prostate cancer (PCa) is dependent on coupled androgen-androgen receptor (AR) signaling for growth and progression. Significant efforts have been made in this research field, as hormonal therapies have greatly improved the survival of patients with metastatic PCa (mPCa). The drug treat...