C-2 phenyl replacements to obtain potent quinoline-based Staphylococcus aureus NorA inhibitors

C-2 phenyl replacements to obtain potent quinoline-based Staphylococcus aureus NorA inhibitors

NorA is the most studied efflux pump of Staphylococcus aureus and is responsible for high level resistance towards fluoroquinolone drugs. Although along the years many NorA efflux pump inhibitors (EPIs) have been reported, poor information is available about structure-activity relationship (SAR) aro...

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Main Authors: Tommaso Felicetti (Author), Gianmarco Mangiaterra (Author), Rolando Cannalire (Author), Nicholas Cedraro (Author), Donatella Pietrella (Author), Andrea Astolfi (Author), Serena Massari (Author), Oriana Tabarrini (Author), Giuseppe Manfroni (Author), Maria Letizia Barreca (Author), Violetta Cecchetti (Author), Francesca Biavasco (Author), Stefano Sabatini (Author)
Format: Book
Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
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3rd Floor Main Library

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