Bone morphogenetic protein 2 inhibits growth differentiation factor 8-induced cell signaling via upregulation of gremlin2 expression in human granulosa-lutein cells

• 主要な著者: Xiaoyan Luo (著者), Hsun-Ming Chang (著者), Yuyin Yi (著者), Yingpu Sun (著者), Peter C. K. Leung (著者)
• フォーマット: 図書
• 出版事項: BMC, 2021-11-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Abstract Background Bone morphogenetic protein 2 (BMP2), growth differentiation factor 8 (GDF8) and their functional receptors are expressed in human ovarian follicles, and these two intrafollicular factors play essential roles in regulating follicle development and luteal function. As BMP antagonis...