The anti-hepatitis B virus and anti-hepatotoxic efficacies of solanopubamine, a rare alkaloid from Solanum schimperianum

• Main Authors: Mohammad K. Parvez (Author), Mohammed S. Al-Dosari (Author), Md. Tabish Rehman (Author), Adnan J. Al-Rehaily (Author), Ali S. Alqahtani (Author), Mohammad F. Alajmi (Author)
• Format: Bog
• Udgivet: Elsevier, 2022-04-01T00:00:00Z.
• Fag: article
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Chronic liver disease caused by hepatitis B virus (HBV) remains an important health issue. Though there are effective HBV-polymerase inhibitors (e.g., lamivudine), their prolonged use leads to emergence of drug-resistant (polymerase mutant) strains. Several herbal formulations and phytochemicals hav...