Alteration of Energy Substrates and ROS Production in Diabetic Cardiomyopathy

• Main Authors: O. Lorenzo (Author), E. Ramírez (Author), B. Picatoste (Author), J. Egido (Author), J. Tuñón (Author)
• Format: Bog
• Udgivet: Hindawi Limited, 2013-01-01T00:00:00Z.
• Fag: article
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Diabetic cardiomyopathy is initiated by alterations in energy substrates. Despite excess of plasma glucose and lipids, the diabetic heart almost exclusively depends on fatty acid degradation. Glycolytic enzymes and transporters are impaired by fatty acid metabolism, leading to accumulation of glucos...