Vesicle-Transported Multidrug Resistance as a Possible Therapeutic Target of Natural Compounds

• Main Authors: Salvatrice Rigogliuso (Author), Alessandra Cusimano (Author), Lucia Condorelli (Author), Manuela Labbozzetta (Author), Gabriella Schiera (Author), Paola Poma (Author), Monica Notarbartolo (Author)
• Format: Book
• Published: MDPI AG, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/Objectives: A key role of extracellular vesicles (EVs) is mediating both cell-cell and cell-stroma communication in pathological/physiological conditions. EVs from resistant tumor cells can transport different molecules like P-glycoprotein (P-gp), acting as a shuttle between donor and rec...