Trypanosoma cruzi High Mobility Group B (TcHMGB) can act as an inflammatory mediator on mammalian cells.

• Hauptverfasser: Pamela Cribb (Verfasst von), Virginia Perdomo (Verfasst von), Victoria L Alonso (Verfasst von), Romina Manarin (Verfasst von), Jorge Barrios-Payán (Verfasst von), Brenda Marquina-Castillo (Verfasst von), Luis Tavernelli (Verfasst von), Rogelio Hernández-Pando (Verfasst von)
• Format: Buch
• Veröffentlicht: Public Library of Science (PLoS), 2017-02-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

BACKGROUND:High Mobility Group B (HMGB) proteins are nuclear architectural factors involved in chromatin remodeling and important nuclear events. HMGBs also play key roles outside the cell acting as alarmins or Damage-associated Molecular Patterns (DAMPs). In response to a danger signal these protei...