Physalin A Inhibits MAPK and NF-κB Signal Transduction Through Integrin αVβ3 and Exerts Chondroprotective Effect

• Main Authors: Rui Lu (Author), Xiaojun Yu (Author), Shuang Liang (Author), Peng Cheng (Author), Zhenggang Wang (Author), Zhi-yi He (Author), Zheng-tao Lv (Author), Junlai Wan (Author), Haokun Mo (Author), Wen-tao Zhu (Author), An-min Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Osteoarthritis (OA) is a common articular ailment presented with cartilage loss and destruction that is common observed in the elderly population. Physalin A (PA), a natural bioactive withanolide, exerts anti-inflammatory residences in more than a few diseases; however, little is known about its eff...