Signals of gastroesophageal reflux disease caused by incretin-based drugs: a disproportionality analysis using the Japanese adverse drug event report database

• Main Authors: Yoshihiro Noguchi (Author), Hayato Katsuno (Author), Anri Ueno (Author), Manami Otsubo (Author), Aki Yoshida (Author), Yuta Kanematsu (Author), Ikuto Sugita (Author), Hiroki Esaki (Author), Tomoya Tachi (Author), Teruo Tsuchiya (Author), Hitomi Teramachi (Author)
• Format: Book
• Published: BMC, 2018-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Incretin-based drugs are important in the treatment of type 2 diabetes. However, among the incretin-based drugs, glucagon-like peptide-1 receptor agonists (GLP-1-RAs) have been reported to cause gastroesophageal reflux disease (GERD)-like symptoms making it difficult to continue...