Mechanism of Rapid Nuclear Factor-E2-Related Factor 2 (Nrf2) Activation via Membrane-Associated Estrogen Receptors: Roles of NADPH Oxidase 1, Neutral Sphingomyelinase 2 and Epidermal Growth Factor Receptor (EGFR)

• Hauptverfasser: Tetsuro Ishii (Verfasst von), Eiji Warabi (Verfasst von)
• Format: Buch
• Veröffentlicht: MDPI AG, 2019-03-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Membrane-associated estrogen receptors (ER)-α36 and G protein-coupled estrogen receptor (GPER) play important roles in the estrogen’s rapid non-genomic actions including stimulation of cell proliferation. Estrogen via these receptors induces rapid activation of transcription factor nuclear...