Effects of FTY720 (Fingolimod) on Proliferation, Differentiation, and Migration of Brain-Derived Neural Stem Cells

• Egile Nagusiak: Botao Tan (Egilea), Zeruxin Luo (Egilea), Yan Yue (Egilea), Yuan Liu (Egilea), Li Pan (Egilea), Lehua Yu (Egilea), Ying Yin (Egilea)
• Formatua: Liburua
• Argitaratua: Hindawi Limited, 2016-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Insufficient proliferation, differentiation, and migration are the main pitfalls of neural stem cells (NSCs) in reparative therapeutics for the central nervous system (CNS) diseases. The potent lipid mediator sphingosine-1-phosphate (S1P) regulates cells' biological behavior broadly in the CNS....