Phenomic landscape and pharmacogenomic implications for HLA region in a Taiwan Han Chinese population

• Main Authors: Wan-Hsuan Chou (Author), Lu-Chun Chen (Author), Henry Sung-Ching Wong (Author), Ching-Hsuan Chao (Author), Hou-Wei Chu (Author), Wei-Chiao Chang (Author)
• Format: Book
• Published: BMC, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The human leukocyte antigen (HLA) genes, exhibiting significant genetic diversity, are associated with susceptibility to various clinical diseases and diverse in drug responses. High costs of HLA sequencing and the population-specific architecture of this genetic region necessita...