Phenomic landscape and pharmacogenomic implications for HLA region in a Taiwan Han Chinese population

• Hauptverfasser: Wan-Hsuan Chou (Verfasst von), Lu-Chun Chen (Verfasst von), Henry Sung-Ching Wong (Verfasst von), Ching-Hsuan Chao (Verfasst von), Hou-Wei Chu (Verfasst von), Wei-Chiao Chang (Verfasst von)
• Format: Buch
• Veröffentlicht: BMC, 2024-05-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Abstract Background The human leukocyte antigen (HLA) genes, exhibiting significant genetic diversity, are associated with susceptibility to various clinical diseases and diverse in drug responses. High costs of HLA sequencing and the population-specific architecture of this genetic region necessita...