New guaiane-type sesquiterpenoid dimers from Artemisia atrovirens and their antihepatoma activity

• Main Authors: Lihua Su (Author), Xintian Zhang (Author), Yunbao Ma (Author), Changan Geng (Author), Xiaoyan Huang (Author), Jing Hu (Author), Tianze Li (Author), Shuang Tang (Author), Cheng Shen (Author), Zhen Gao (Author), Xuemei Zhang (Author), Ji-Jun Chen (Author)
• Format: Book
• Published: Elsevier, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Leading by cytotoxicity against HepG2 cells, bioactivity-guided fractionation of the EtOAc fraction from Artemisia atrovirens led to the isolation of 18 new guaianolide dimers, artematrolides A-R and lavandiolides A, B, C, H, and J. Eight compounds (1, 4, 10, 12, 13, and 19-21) were unambiguously co...